SCHEMBL531620

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5342897	0.81	PARP1 (0.57)	ALDH1A1HSD17B10TDP1PARP1USP2
	SCHEMBL532347	0.81	PARP1 (0.57)	ALDH1A1HSD17B10TDP1PARP1USP2
	SCHEMBL5188341	0.81	PARP1 (0.57)	ALDH1A1HSD17B10TDP1PARP1USP2
	SCHEMBL532921	0.78	USP2 (0.48)	HSD17B10PARP1USP2GAAMEN1
	SCHEMBL2288001	0.77	CA2 (0.50)	ALDH1A1HSD17B10TDP1PARP1USP2
	SCHEMBL2163564	0.76	L3MBTL1 (0.51)	HSD17B10USP2GAAMEN1KMT2A
	SCHEMBL7155529	0.73	PARP1 (0.62)	ALDH1A1HSD17B10PARP1USP2GAA
	SCHEMBL8117465	0.73	L3MBTL1 (0.48)	HSD17B10PARP1USP2GAAMEN1
	SCHEMBL2165889	0.72	L3MBTL1 (0.47)	HSD17B10USP2GAAMEN1KMT2A
	SCHEMBL15651034	0.70	ALDH1A1 (0.39)	ALDH1A1HSD17B10TDP1PTGS2NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.