Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341837 | 0.86 | NSD2 (0.41) | NSD2KCNH2NR3C2ALDH1A1EGLN1 | |
| SCHEMBL5317641 | 0.83 | MEN1 (0.42) | NSD2KCNH2 | |
| SCHEMBL3116828 | 0.79 | SIGMAR1 (0.43) | KCNH2KDM1AHRH2HRH1HRH3 | |
| Hydrochloric Acid SCHEMBL3125607 | 0.78 | SIGMAR1 (0.42) | KCNH2KDM1AHRH2HRH1HRH3 | |
| SCHEMBL4516189 | 0.78 | HRH1 (0.36) | KCNH2KDM1AHRH2HRH1HRH3 | |
| SCHEMBL5314444 | 0.77 | NSD2 (0.41) | NSD2KCNH2NR3C2ALDH1A1 | |
| SCHEMBL5319877 | 0.77 | KCNH2 (0.39) | NSD2KCNH2NR3C2EGLN1HRH2 | |
| SCHEMBL4520264 | 0.77 | HRH2 (0.46) | KCNH2ALDH1A1HRH2HRH1HRH3 | |
| SCHEMBL5316853 | 0.76 | FAAH (0.40) | NSD2KCNH2 | |
| SCHEMBL5316884 | 0.76 | KCNH2 (0.38) | NSD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |