Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341837 | 0.87 | NSD2 (0.41) | MEN1NPC1KMT2AMCHR1NSD2 | |
| SCHEMBL5316232 | 0.83 | NSD2 (0.42) | NSD2KCNH2 | |
| SCHEMBL5319745 | 0.82 | KMT2A (0.43) | MEN1NPC1KMT2AL3MBTL1KCNH2 | |
| SCHEMBL5317617 | 0.82 | CCR5 (0.41) | MEN1KMT2AL3MBTL1OPRM1CCR5 | |
| SCHEMBL3127651 | 0.81 | KCNH2 (0.40) | SIGMAR1L3MBTL1KCNH2KCNJ1 | |
| SCHEMBL5316853 | 0.80 | FAAH (0.40) | MEN1KMT2ANSD2SIGMAR1KCNH2 | |
| SCHEMBL5316884 | 0.80 | KCNH2 (0.38) | MEN1KMT2ANSD2SIGMAR1ACHE | |
| SCHEMBL5317478 | 0.80 | CCR3 (0.54) | NAMPTSIGMAR1TMEM97OPRD1 | |
| SCHEMBL4512066 | 0.79 | KCNH2 (0.41) | MEN1NPC1L3MBTL1KCNH2OPRM1 | |
| SCHEMBL5535795 | 0.79 | HRH1 (0.46) | MEN1SIGMAR1KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |