SCHEMBL5316347

SCHEMBL5316347

CC(C)CSc1cccc(C(N)=O)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 7/20 0.47
MAP1LC3B Q9GZQ8 1/20 0.46
MAP1LC3A Q9H492 1/20 0.46
APEX1 P27695 1/20 0.45
MAOA P21397 2/20 0.44
PARP15 Q460N3 1/20 0.43
PARP10 Q53GL7 1/20 0.43
MTNR1A P48039 6/20 0.42
MTNR1B P49286 6/20 0.42
KIF11 P52732 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5315809 0.85 APEX1 (0.63) MAP1LC3BMAP1LC3AAPEX1MAOAMTNR1A
SCHEMBL7696215 0.81 EPHX2 (0.55) PARP1MAP1LC3BMAP1LC3AAPEX1PARP15
SCHEMBL17048425 0.81 MTNR1A (0.49) MAP1LC3BMAP1LC3AAPEX1MTNR1AMTNR1B
SCHEMBL1397499 0.75 PARP1 (0.57) PARP1PARP15PARP10CYP1A2CYP2C9
SCHEMBL29378080 0.75 HSD17B10 (0.67) PARP1APEX1PARP15PARP10KIF11
SCHEMBL28443286 0.75 HSD17B10 (0.67) PARP1APEX1PARP15PARP10KIF11
SCHEMBL18807057 0.75 PARP1 (0.57) PARP1APEX1PARP15PARP10CYP1A2
SCHEMBL30633020 0.74 PARP1 (0.47) PARP1APEX1PARP15PARP10KIF11
SCHEMBL5313145 0.74 MAOA (0.50) MAP1LC3BMAP1LC3AMAOAMTNR1AMTNR1B
SCHEMBL10919344 0.72 MTNR1A (0.40) MAP1LC3BMAP1LC3AAPEX1MAOAMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed