Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311221 | 0.92 | ATM (0.66) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL6511477 | 0.84 | KMT2A (0.52) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL5316465 | 0.83 | KMT2A (0.55) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL6506821 | 0.83 | KMT2A (0.50) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL6508537 | 0.83 | KMT2A (0.50) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL5314170 | 0.81 | KMT2A (0.48) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL10762060 | 0.78 | KMT2A (0.61) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL6507280 | 0.78 | KMT2A (0.52) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL10921521 | 0.77 | KMT2A (0.67) | ATMKMT2AMEN1USP2MAPT | |
| SCHEMBL7602852 | 0.77 | GAA (0.60) | KMT2AMEN1GAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |