Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017764 | 0.88 | TLR8 (0.49) | PTGS2TLR8SOAT1CNR2MAPT | |
| SCHEMBL6835641 | 0.88 | PTGS2 (0.41) | PTGS2TLR8MAPT | |
| SCHEMBL18758015 | 0.85 | PTGS2 (0.49) | PTGS2TLR8CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL30417186 | 0.85 | PTGS2 (0.49) | PTGS2TLR8CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL5316461 | 0.83 | PTGS2 (0.50) | PTGS2TLR8CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL25738323 | 0.83 | PTGS2 (0.50) | PTGS2TLR8CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL29056062 | 0.82 | PTGS2 (0.38) | PTGS2TLR8MAPT | |
| SCHEMBL28407380 | 0.82 | KDM4E (0.38) | PTGS2TLR8MAPT | |
| SCHEMBL20678469 | 0.81 | TLR8 (0.53) | PTGS2TLR8CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL2607673 | 0.80 | TLR8 (0.50) | PTGS2TLR8CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101155896-B | Organic electroluminescent device | MERCK PATENT GMBH | 2012-08-29 | — | — | CN | disclosed |
| EP-0451735-A2 | Improved elastomeric layer for multilayer tonable photosensitive elements | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |