Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240400 | 0.83 | KMT2A (0.51) | LMNANPC1SMN1; SMN2MAPTTSHR | |
| SCHEMBL24508981 | 0.82 | LMNA (0.52) | LMNANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL14495066 | 0.82 | LMNA (0.47) | LMNANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL5055096 | 0.80 | CES2 (0.51) | LMNANPC1SMN1; SMN2CES2CES1 | |
| SCHEMBL13116531 | 0.79 | CYP4F2 (0.36) | SMN1; SMN2MAPTTSHRALDH1A1SLC6A2 | |
| SCHEMBL2087207 | 0.77 | MAOB (0.40) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL3730123 | 0.76 | CES2 (0.54) | LMNANPC1SMN1; SMN2CES2CES1 | |
| SCHEMBL1338330 | 0.76 | LMNA (0.52) | LMNANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL1167035 | 0.76 | NPC1 (0.55) | LMNANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL10604429 | 0.75 | LMNA (0.51) | LMNANPC1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062797-A1 | AMINO-SUBSTITUTED AZO-HETEROCYCLIC COMPOUNDS FOR TREATING INFLAMMATORY CONDITIONS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |