Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356694 | 0.88 | LPL (0.55) | LPLLIPGALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29640063 | 0.88 | LPL (0.55) | LPLLIPGALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1641031 | 0.86 | SMN1; SMN2 (0.54) | LPLLIPGALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL3028131 | 0.86 | LIPG (0.45) | LPLLIPGSIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2072274 | 0.85 | SMN1; SMN2 (0.52) | LPLLIPGALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL722120 | 0.85 | LPL (0.52) | LPLLIPGSIGMAR1BRD4TDP1 | |
| SCHEMBL585841 | 0.85 | NCF1 (0.54) | LPLLIPGCXCR4BRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15845597 | 0.84 | NCF1 (0.52) | LPLLIPGCXCR4BRD4ALDH1A1 | |
| SCHEMBL15981298 | 0.83 | CXCR4 (0.50) | LPLLIPGSIGMAR1CXCR4MEN1 | |
| SCHEMBL31341362 | 0.82 | LPL (0.49) | LPLLIPGSIGMAR1BRD4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812439-A2 | KINASE INHIBITORS | Takeda San Diego, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006044687-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-04-27 | — | — | WO | disclosed |