Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444359 | 0.83 | LOXL2 (0.57) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL1695664 | 0.83 | LOXL2 (0.57) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL6563716 | 0.81 | CYP2C9 (0.59) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL22250101 | 0.81 | EPHX2 (0.55) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL5315293 | 0.81 | LOXL2 (0.60) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL10194672 | 0.81 | TGM2 (0.63) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL7934897 | 0.79 | EPHX2 (0.52) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL19049390 | 0.79 | LOXL2 (0.56) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL5315364 | 0.79 | EPHX2 (0.52) | EPHX2LOXL2SAE1UBA2CYP19A1 | |
| SCHEMBL15630672 | 0.79 | EPHX2 (0.52) | EPHX2LOXL2SAE1UBA2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |