Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.73 |
| ▸ | APP | P05067 | 7/20 | 0.70 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.69 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.69 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951837 | 1.00 | NFE2L2 (0.73) | NFE2L2APPTTRCXCL12CXCR4 | |
| SCHEMBL671150 | 0.89 | TTR (0.85) | NFE2L2APPTTRTYRALOX5 | |
| SCHEMBL671149 | 0.89 | TTR (0.85) | NFE2L2APPTTRTYRALOX5 | |
| SCHEMBL17732299 | 0.89 | TTR (0.85) | NFE2L2APPTTRTYRALOX5 | |
| SCHEMBL30807100 | 0.89 | TTR (0.85) | NFE2L2APPTTRTYRALOX5 | |
| SCHEMBL9616786 | 0.86 | TTR (0.80) | NFE2L2APPTTRTYRALOX5 | |
| SCHEMBL5315843 | 0.86 | TTR (0.80) | NFE2L2APPTTRTYRALOX5 | |
| SCHEMBL3220833 | 0.85 | APP (0.84) | NFE2L2APPCXCL12CXCR4TYR | |
| SCHEMBL3220819 | 0.85 | APP (0.84) | NFE2L2APPCXCL12CXCR4TYR | |
| SCHEMBL4938984 | 0.84 | NFE2L2 (0.75) | NFE2L2APPTTRTYRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276172-A1 | Single step microwave induced process for the preparation of substituted stilbenes and its analogs | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-11-29 | — | — | US | disclosed |
| WO-2007110883-A1 | A SINGLE STEP MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED STILBENES AND ITS ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276172-A1 | Single step microwave induced process for the preparation of substituted stilbenes and its analogs | HRH3, HPD, TET2 | NFE2L2 2018/4885APP 2318/4885TTR 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.