Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320413 | 0.81 | MEN1 (0.41) | L3MBTL1MAPTHPGDMEN1KMT2A | |
| SCHEMBL15836991 | 0.79 | CA12 (0.48) | ACHEL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL5316585 | 0.77 | L3MBTL1 (0.51) | ACHEL3MBTL1MAPTHPGDMEN1 | |
| SCHEMBL5317250 | 0.77 | ACHE (0.50) | ACHEL3MBTL1MAPTHPGDMEN1 | |
| SCHEMBL5318993 | 0.74 | ACHE (0.50) | ACHEL3MBTL1MAPTHPGDMEN1 | |
| SCHEMBL3788515 | 0.74 | MEN1 (0.40) | MAPTHPGDMEN1KMT2ACYP2C19 | |
| SCHEMBL10639618 | 0.73 | TTR (0.49) | L3MBTL1MAPTHPGDALDH1A1MAPK1 | |
| SCHEMBL29862129 | 0.73 | — | — | |
| SCHEMBL321951 | 0.73 | — | — | |
| SCHEMBL14577511 | 0.73 | MEN1 (0.77) | MAPTHPGDMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |