SCHEMBL5317296

SCHEMBL5317296

O=C(c1ccccc1)c1cccc(SC2CCCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TXN P10599 1/20 0.47
OPRM1 P35372 1/20 0.45
OPRK1 P41145 1/20 0.45
KCNH2 Q12809 1/20 0.45
GAA P10253 2/20 0.44
POLB P06746 1/20 0.44
ELANE P08246 1/20 0.44
PBRM1 Q86U86 1/20 0.44
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 2/20 0.43
GRIK1 P39086 1/20 0.43
GRIA2 P42262 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
DDB1 Q16531 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6484438 0.88 HPGD (0.56) OPRM1OPRK1KCNH2GAAPOLB
SCHEMBL2568668 0.86 HPGD (0.58) OPRM1OPRK1KCNH2GAAALDH1A1
SCHEMBL28188608 0.83 OPRM1 (0.55) OPRM1OPRK1KCNH2GAAGRIK1
SCHEMBL2792773 0.81 ALDH1A1 (0.49) TDP1OPRM1OPRK1KCNH2NPC1
SCHEMBL28188078 0.81 OPRM1 (0.56) OPRM1OPRK1KCNH2GAAGRIK1
SCHEMBL27950377 0.79 HPGD (0.41) L3MBTL1OPRM1OPRK1KCNH2GAA
SCHEMBL5316486 0.79 HPGD (0.55) ATML3MBTL1GAAPOLBRAB9A
SCHEMBL21241853 0.79 HPGD (0.61) OPRM1OPRK1KCNH2GAAALDH1A1
SCHEMBL30288407 0.79 HPGD (0.61) OPRM1OPRK1KCNH2GAAALDH1A1
SCHEMBL19890876 0.78 MAOA (0.55) ATMPOLBALDH1A1GRIK1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed