Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2HSD17B10KDM4ETSHR | |
| SCHEMBL3398965 | 0.79 | CYP19A1 (0.39) | SLC6A2SLC6A4SLC6A3HSD17B10KDM4E | |
| SCHEMBL6631529 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2TSHRTRIM24TRIM33 | |
| SCHEMBL26999257 | 0.79 | ACP3 (0.41) | GABRA1GABRB2HSD17B10TSHRALDH1A1 | |
| SCHEMBL26999259 | 0.79 | TSHR (0.39) | SLC6A2SLC6A4SLC6A3GABRA1GABRB2 | |
| SCHEMBL6501428 | 0.79 | GAA (0.41) | SLC6A2SLC6A4SLC6A3HSD17B10KDM4E | |
| SCHEMBL8549265 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2KDM4ETSHRTRIM24 | |
| SCHEMBL14125895 | 0.79 | GABRA1 (0.42) | SLC6A4GABRA1GABRB2HSD17B10TSHR | |
| SCHEMBL1515763 | 0.77 | SLC6A3 (0.58) | SLC6A2SLC6A4SLC6A3HSD17B10KDM4E | |
| SCHEMBL16062471 | 0.77 | CYP1A2 (0.42) | SLC6A2SLC6A4SLC6A3SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841747-A1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK Corporation (KR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006075888-A1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK CORPORATION (KR) | 2006-07-20 | — | — | WO | disclosed |