Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812737 | 0.82 | CES2 (0.47) | RAB9AKMT2AKDM4ENPC1 | |
| SCHEMBL4473850 | 0.81 | CYP19A1 (0.64) | CYP19A1RAB9ACYP3A4CYP3A5 | |
| SCHEMBL10952238 | 0.81 | RAB9A (0.46) | CYP19A1RAB9AKMT2APOLBCYP1A1 | |
| SCHEMBL29226497 | 0.80 | CYP19A1 (0.53) | CYP19A1RAB9AKMT2APOLBKDM4E | |
| SCHEMBL29226492 | 0.80 | CYP19A1 (0.53) | CYP19A1RAB9AKMT2APOLBKDM4E | |
| SCHEMBL30927957 | 0.80 | CYP19A1 (0.53) | CYP19A1RAB9AKMT2APOLBKDM4E | |
| SCHEMBL30927949 | 0.80 | CYP19A1 (0.53) | CYP19A1RAB9AKMT2APOLBKDM4E | |
| Bromide SCHEMBL6282386 | 0.79 | RAB9A (0.45) | CYP19A1RAB9AKMT2APOLBCYP1A1 | |
| SCHEMBL4558274 | 0.79 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11627640 | 0.78 | CYP19A1 (0.51) | CYP19A1RAB9AKMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841747-A1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK Corporation (KR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006075888-A1 | OXAZOLE HYDROXAMIC ACID DERIVATIVES AND USE THEREOF | SK CORPORATION (KR) | 2006-07-20 | — | — | WO | disclosed |