SCHEMBL5317333

SCHEMBL5317333

CCCCCCCCCCCCCCCCCC(=O)C(O)C[N+](C)(C)C

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
MAPK1 P28482 2/20 0.47
CYP1A2 P05177 2/20 0.47
TP53 P04637 2/20 0.47
TSHR P16473 2/20 0.47
MEN1 O00255 1/20 0.47
GMNN O75496 1/20 0.47
LMNA P02545 1/20 0.47
HSP90AA1 P07900 1/20 0.47
MAPT P10636 1/20 0.47
BLM P54132 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
CYP2C9 P11712 1/20 0.47
HIF1A Q16665 1/20 0.47
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5319042 1.00 CES2 (0.52) CES2MAPK1CYP1A2TP53TSHR
SCHEMBL9632303 1.00 CES2 (0.52) CES2MAPK1CYP1A2TP53TSHR
SCHEMBL200399 1.00 CES2 (0.52) CES2MAPK1CYP1A2TP53TSHR
SCHEMBL198090 1.00 CES2 (0.52) CES2MAPK1CYP1A2TP53TSHR
SCHEMBL200766 1.00 CES2 (0.52) CES2MAPK1CYP1A2TP53TSHR
Iodide SCHEMBL9630545 0.98 CES2 (0.50) CES2MAPK1CYP1A2TP53TSHR
Hydrochloric Acid SCHEMBL7561213 0.98 CES2 (0.50) CES2MAPK1CYP1A2TP53TSHR
Hydrochloric Acid SCHEMBL16990768 0.98 CES2 (0.50) CES2MAPK1CYP1A2TP53TSHR
Hydrochloric Acid SCHEMBL9632302 0.98 CES2 (0.50) CES2MAPK1CYP1A2TP53TSHR
Iodide SCHEMBL9630733 0.98 CES2 (0.50) CES2MAPK1CYP1A2TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250336540-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2025-10-30 US claimed
US-12292445-B2 Methods of selecting subjects for treatment with metabolomic modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-06 US claimed
EP-4515242-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN Pharmaceutica NV (BE) 2025-03-05 EP claimed
WO-2023209218-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2023-11-02 WO claimed
US-20210407677-A1 FATTY ACID AND KREBS CYCLE METABOLOMIC MEASURES FOR TREATMENT OF HEAD INJURY NORTHWESTERN UNIVERSITY (US) 2021-12-30 US claimed
US-20210364526-A1 METHODS OF SELECTING SUBJECTS FOR TREATMENT WITH METABOLOMIC MODULATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-11-25 US claimed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP claimed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP claimed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO claimed
EP-0206947-B1 PHARMACEUTICAL COMPOSITION CONTAINING CHOLINE ESTER SALTS FOR ENHANCING GASTROINTESTINAL TRACT ABSORPTION MERCK & CO. INC. (US) 1992-04-15 EP claimed
EP-0214898-B1 CHOLINE ESTERS AS ABSORPTION-ENHANCING AGENTS FOR DRUG DELIVERY THROUGH MUCOUS MEMBRANES OF THE NASAL, BUCCAL, SUBLINGUAL AND VAGINAL CAVITIES MERCK & CO. INC. (US) 1992-03-11 EP claimed
US-4973579-A VIRICIDES MERCK & CO., INC. (US) 1990-11-27 US claimed
US-4963556-A ANTIVIRAL AGENTS MERCK & CO., INC. (US) 1990-10-16 US claimed
US-4835138-A Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities MERCK & CO., INC. (US) 1989-05-30 US claimed
US-4822773-A Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts MERCK & CO., INC. (US) 1989-04-18 US claimed
US-4729989-A Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts MERCK & CO., INC. (US) 1988-03-08 US claimed
US-4692441-A B-LACTAM ANTIBIOTICS MERCK & CO., INC. (US) 1987-09-08 US claimed
EP-0214898-A2 Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities MERCK & CO. INC. (US) 1987-03-18 EP claimed
EP-0206947-A2 Pharmaceutical composition containing choline ester salts for enhancing gastrointestinal tract absorption MERCK & CO. INC. (US) 1986-12-30 EP claimed
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM UNIV CALIFORNIA (US) 2025-12-11 US disclosed
US-20250336540-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2025-10-30 US disclosed
US-12292445-B2 Methods of selecting subjects for treatment with metabolomic modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-06 US disclosed
EP-4515242-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN Pharmaceutica NV (BE) 2025-03-05 EP disclosed
US-20240257973-A1 DISEASE SPECTRUM CLASSIFICATION PATIENTSLIKEME LLC (US) 2024-08-01 US disclosed
US-11894139-B1 Disease spectrum classification PATIENTSLIKEME LLC (US) 2024-02-06 US disclosed
US-20230404957-A1 Pet Food Compositions HILL'S PET NUTRITION, INC. (US) 2023-12-21 US disclosed
US-20230371552-A1 Pet Food Compositions HILL'S PET NUTRITION, INC. (US) 2023-11-23 US disclosed
WO-2023209218-A1 METABOLITE PREDICTORS FOR LUNG CANCER JANSSEN PHARMACEUTICA NV (BE) 2023-11-02 WO disclosed
EP-3419753-B1 QUATERNARY AMMONIUM SULFUR-CONTAINING BINUCLEAR MOLYBDATE SALTS AS LUBRICANT ADDITIVES VANDERBILT CHEMICALS LLC (US) 2023-07-12 EP disclosed
US-20220102000-A1 PREDICTING BLOOD METABOLITES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-03-31 US disclosed
CN-110478331-B Drug-loaded bacteria outer membrane vesicle and preparation method and application thereof 中国医学科学院医药生物技术研究所 2022-02-18 CN disclosed
US-20210407677-A1 FATTY ACID AND KREBS CYCLE METABOLOMIC MEASURES FOR TREATMENT OF HEAD INJURY NORTHWESTERN UNIVERSITY (US) 2021-12-30 US disclosed
US-20210364526-A1 METHODS OF SELECTING SUBJECTS FOR TREATMENT WITH METABOLOMIC MODULATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-11-25 US disclosed
US-10590364-B2 Quaternary ammonium sulfur-containing binuclear molybdate salts as lubricant additives VANDERBILT CHEMICALS, LLC (US) 2020-03-17 US disclosed
US-20190310269-A1 SYSTEMS AND METHODS FOR MEASURING OBESITY USING METABOLOME ANALYSIS HUMAN LONGEVITY, INC. 2019-10-10 US disclosed
EP-3419753-A1 QUATERNARY AMMONIUM SULFUR-CONTAINING BINUCLEAR MOLYBDATE SALTS AS LUBRICANT ADDITIVES Vanderbilt Chemicals, LLC (US) 2019-01-02 EP disclosed
US-20180327685-A1 Quaternary Ammonium Sulfur-Containing Binuclear Molybdate Salts as Lubricant Additives VANDERBILT CHEMICALS LLC (US) 2018-11-15 US disclosed
US-10059901-B2 Quaternary ammonium sulfur-containing binuclear molybdate salts as lubricant additives VANDERBILT CHEMICALS, LLC (US) 2018-08-28 US disclosed
WO-2017146939-A1 QUATERNARY AMMONIUM SULFUR-CONTAINING BINUCLEAR MOLYBDATE SALTS AS LUBRICANT ADDITIVES VANDERBILT CHEMICALS, LLC (US) 2017-08-31 WO disclosed
US-20170240838-A1 QUATERNARY AMMONIUM SULFUR-CONTAINING BINUCLEAR MOLYBDATE SALTS AS LUBRICANT ADDITIVES VANDERBILT CHEMICALS, LLC (US) 2017-08-24 US disclosed
WO-2007079252-A2 SUSTAINED RELEASE PHARMACEUTICAL COMPOSITIONS AMPHASTAR PHARMACEUTICALS, INC. (US) 2007-07-12 WO disclosed
US-5955584-A NON-PROTEIN ANTIGEN COMPOSED OF STEROID COMPONENT WITH 3 BETA HYDROXY OR 3 KETO GROUP AND QUATERNARY AMMONIUM SALT; FOR THERAPY AND IMMUNOASSAY DIAGNOSIS CHARTER VENTURES (US) 1999-09-21 US disclosed
US-5811248-A Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof CHARTER VENTURES (US) 1998-09-22 US disclosed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP disclosed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP disclosed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO disclosed
EP-0206947-B1 PHARMACEUTICAL COMPOSITION CONTAINING CHOLINE ESTER SALTS FOR ENHANCING GASTROINTESTINAL TRACT ABSORPTION MERCK & CO. INC. (US) 1992-04-15 EP disclosed
EP-0214898-B1 CHOLINE ESTERS AS ABSORPTION-ENHANCING AGENTS FOR DRUG DELIVERY THROUGH MUCOUS MEMBRANES OF THE NASAL, BUCCAL, SUBLINGUAL AND VAGINAL CAVITIES MERCK & CO. INC. (US) 1992-03-11 EP disclosed
US-4973579-A VIRICIDES MERCK & CO., INC. (US) 1990-11-27 US disclosed
US-4963556-A ANTIVIRAL AGENTS MERCK & CO., INC. (US) 1990-10-16 US disclosed
US-4835138-A Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities MERCK & CO., INC. (US) 1989-05-30 US disclosed
US-4822773-A Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts MERCK & CO., INC. (US) 1989-04-18 US disclosed
US-4729989-A Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts MERCK & CO., INC. (US) 1988-03-08 US disclosed
US-4692441-A B-LACTAM ANTIBIOTICS MERCK & CO., INC. (US) 1987-09-08 US disclosed
EP-0214898-A2 Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities MERCK & CO. INC. (US) 1987-03-18 EP disclosed
EP-0206947-A2 Pharmaceutical composition containing choline ester salts for enhancing gastrointestinal tract absorption MERCK & CO. INC. (US) 1986-12-30 EP disclosed
EP-0206947-A2 Pharmaceutical composition containing choline ester salts for enhancing gastrointestinal tract absorption MERCK & CO. INC. (US) 1986-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM CYP27A1, LIPC, CYP46A1 CES2 464/4885MAPK1 3368/4885CYP1A2 504/4885
US-10590364-B2 Quaternary ammonium sulfur-containing binuclear molybdate salts as lubricant additives ATXN10, MDM4, OR10J3 CES2 4694/4885MAPK1 1883/4885CYP1A2 3780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.