Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314598 | 0.90 | KCNH2 (0.53) | KCNH2EPHX2MEN1KMT2AHRH3 | |
| SCHEMBL5316933 | 0.88 | KCNH2 (0.47) | KCNH2POLBMEN1HRH3HTR2A | |
| SCHEMBL5315724 | 0.85 | KCNH2 (0.56) | KCNH2KMT2AKDM4EHTTHRH3 | |
| SCHEMBL5319103 | 0.85 | KCNH2 (0.49) | KCNH2MEN1KDM4EALDH1A1LMNA | |
| SCHEMBL5318102 | 0.84 | KCNH2 (0.52) | KCNH2POLBHRH3 | |
| SCHEMBL5314630 | 0.84 | KCNH2 (0.55) | KCNH2MEN1KMT2AHRH3 | |
| SCHEMBL5316611 | 0.83 | KCNH2 (0.51) | KCNH2POLBHRH3 | |
| SCHEMBL5316699 | 0.81 | CA1 (0.44) | KCNH2EPHX2POLBCCR2VNN1 | |
| SCHEMBL5316196 | 0.81 | KCNH2 (0.48) | KCNH2POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL5315301 | 0.81 | KCNH2 (0.48) | FAAHKCNH2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |