Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | HRH2 | P25021 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316933 | 0.96 | KCNH2 (0.47) | KCNH2KCNA5MEN1HRH2HRH1 | |
| SCHEMBL5314900 | 0.95 | KCNA5 (0.55) | KCNH2KCNA5HTR1ADRD2HTR7 | |
| SCHEMBL5315724 | 0.91 | KCNH2 (0.56) | KCNH2HRH2HRH1HRH3CACNA1B | |
| SCHEMBL5318090 | 0.90 | KCNH2 (0.52) | KCNH2KCNA5MEN1HRH2HRH1 | |
| SCHEMBL5314630 | 0.89 | KCNH2 (0.55) | KCNH2KCNA5MEN1HRH2HRH1 | |
| SCHEMBL5314570 | 0.89 | HTR1A (0.48) | MEN1HRH1HTR1ADRD2HTR7 | |
| SCHEMBL5316192 | 0.88 | HTT (0.52) | MEN1HTR1ADRD2HTR7HTR6 | |
| SCHEMBL5316850 | 0.88 | HTR1A (0.49) | KCNA5MEN1HRH1HTR1ADRD2 | |
| SCHEMBL5319026 | 0.88 | HTR1A (0.49) | KCNA5MEN1HRH1HTR1ADRD2 | |
| SCHEMBL5315427 | 0.87 | MEN1 (0.47) | KCNH2KCNA5MEN1CACNA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |