Methoxymethane

Methoxymethane

SCHEMBL5317367

CC(=O)Oc1ccc(NCCOc2c(Cl)cc(F)cc2Cl)cc1C(=O)O.COC

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.43
TTR P02766 1/20 0.37
KDM4E B2RXH2 6/20 0.37
PTGS1 P23219 2/20 0.37
PTGS2 P35354 2/20 0.37
ALDH1A1 P00352 5/20 0.36
MAPT P10636 3/20 0.36
GFER P55789 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
GGT1 P19440 1/20 0.36
BLM P54132 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5317363 0.91 EGFR (0.38) KDM4EALDH1A1MAPTTDP1HPGD
Methoxymethane SCHEMBL5317339 0.84 MRGPRX4 (0.49) CFDKDM4EMAPTTDP1TSHR
Methoxymethane SCHEMBL5317331 0.84 PPARA (0.47) CFDKDM4EPTGS1PTGS2ALDH1A1
Methoxymethane SCHEMBL5317705 0.83 KMT2A (0.45) CFDKDM4EALDH1A1MAPTHPGD
Methoxymethane SCHEMBL5321426 0.81 KMT2A (0.49) CFDKDM4EALDH1A1MAPTCYP1A2
SCHEMBL3420712 0.81 PPARA (0.50) TTRKDM4EALDH1A1MAPTTDP1
Methoxymethane SCHEMBL5318378 0.81 PPARA (0.47) CFDKDM4EPTGS1PTGS2ALDH1A1
Methoxymethane SCHEMBL5317742 0.81 CFD (0.46) CFDKDM4EPTGS1PTGS2ALDH1A1
SCHEMBL5316326 0.81 CFD (0.46) CFDKDM4EALDH1A1MAPTHPGD
Methoxymethane SCHEMBL5316071 0.80 KMT2A (0.46) CFDKDM4EMAPTHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007119984-A1 SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM NEUROTECH CO., LTD. (KR) 2007-10-25 WO disclosed