Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414969 | 0.93 | NSD2 (0.52) | NSD2GSK3BCA1CA2KMT2A | |
| SCHEMBL10795881 | 0.86 | HDAC4 (0.54) | HDAC4ALDH1A1MLYCDDRD2PDK2 | |
| SCHEMBL8160105 | 0.83 | HDAC4 (0.45) | NSD2HDAC4MLYCDDRD2PDK2 | |
| SCHEMBL5318145 | 0.81 | NSD2 (0.60) | NSD2GSK3BCA1CA2KMT2A | |
| SCHEMBL7329778 | 0.79 | ESRRG (0.65) | NSD2CA2KMT2AMEN1NPC1 | |
| SCHEMBL23470992 | 0.79 | HDAC4 (0.49) | HDAC4MLYCDDRD2PDK2 | |
| SCHEMBL11748046 | 0.79 | CDK4 (0.50) | GSK3BHDAC4ALDH1A1MLYCDDRD2 | |
| SCHEMBL23116831 | 0.79 | ESRRG (0.56) | CA1CA2HDAC4ALDH1A1MAPT | |
| SCHEMBL10933810 | 0.78 | NSD2 (0.55) | NSD2GSK3BCA1CA2KMT2A | |
| SCHEMBL21332320 | 0.78 | RAB9A (0.58) | NSD2KMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |