Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105192 | 0.90 | P2RY12 (0.31) | — | |
| SCHEMBL4001854 | 0.83 | ALDH1A1 (0.40) | ALDH1A1NPSR1KDM4EHPGDLMNA | |
| SCHEMBL4103363 | 0.73 | P2RY12 (0.31) | — | |
| SCHEMBL4112561 | 0.71 | PDXK (0.35) | — | |
| SCHEMBL4099671 | 0.70 | — | — | |
| SCHEMBL16000815 | 0.66 | NOTUM (0.46) | ALDH1A1NPSR1KDM4EHPGDLMNA | |
| SCHEMBL30540779 | 0.65 | ALDH1A1 (0.39) | ALDH1A1NPSR1 | |
| SCHEMBL7052545 | 0.65 | ALDH1A1 (0.39) | ALDH1A1NPSR1 | |
| SCHEMBL27697969 | 0.64 | NPC1 (0.49) | ALDH1A1KDM4EHPGD | |
| SCHEMBL4103027 | 0.64 | P2RY12 (0.42) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |