SCHEMBL5317698

SCHEMBL5317698

CCN(CC)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
IDO1 P14902 1/20 0.44
TP53 P04637 1/20 0.44
AGXT P21549 1/20 0.43
BCHE P06276 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10477327 0.90 TSHR (0.47) TSHRIDO1TP53AGXTBCHE
SCHEMBL14617699 0.80 TSHR (0.46) TSHRIDO1TP53AGXTBCHE
SCHEMBL4945866 0.79 DRD2 (0.44) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL1703710 0.79 MAOA (0.42) L3MBTL1CHRM2HTR1AADRA2ACHRM1
SCHEMBL10797055 0.79 TSHR (0.50) TSHRIDO1AGXTBCHEALDH1A1
SCHEMBL10517766 0.77 TSHR (0.37) TSHRBCHEALDH1A1CYP3A4CYP2C9
SCHEMBL10773335 0.77 KCNH2 (0.51) BCHEOPRM1DRD3KCNH2
SCHEMBL12812879 0.77 IDO1 (0.55) IDO1BCHECYP2C19LMNA
SCHEMBL12514967 0.77 ALDH1A1 (0.55) ALDH1A1
SCHEMBL24632162 0.76 TSHR (0.52) TSHRIDO1TP53AGXTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5245024-A Cellulose chromatography support LOYOLA UNIVERSITY OF CHICAGO (US) 1993-09-14 US claimed
JP-1216941-A None JP disclosed
CN-103869613-A Colored hardening composite, pattern hardeninig colored layer using same, colored filter and liquid crystal display device SUMITOMO CHEMICAL CO 2014-06-18 CN disclosed
CN-101598897-B Colored curable composition, pattern-cured colored layer using same, color filter, and liquid crystal display device SUMITOMO CHEMICAL CO 2014-05-14 CN disclosed
CN-101750890-A Photosensitive black-colored resin composition, black matrix substrate, and manufacturing method of color filter SUMITOMO CHEMICAL CO 2010-06-23 CN disclosed
CN-101598897-A colored curable composition SUMITOMO CHEMICAL CO (JP) 2009-12-09 CN disclosed
WO-2007139312-A1 COLORED NEGATIVE PHOTORESIST COMPOSITION, COLORED PATTERN COMPRISING THE SAME, AND METHOD FOR PRODUCING THE COLORED PATTERN DONGWOO FINE-CHEM. CO., LTD. (KR) 2007-12-06 WO disclosed
CN-100351656-C Coloration-photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2007-11-28 CN disclosed
CN-100350281-C Radioactive-ray sensitive composition for colour optical filter, colouring-layer for mation method and use JSR CORP (JP) 2007-11-21 CN disclosed
CN-1257434-C Photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2006-05-24 CN disclosed
CN-1508574-A Radioactive-ray sensitive composition for colour optical filter, colouring-layer for mation method and use JSR株式会社 2004-06-30 CN disclosed
CN-1504777-A Coloration-photosensitive resin composition 住友化学工业株式会社 2004-06-16 CN disclosed
CN-1435731-A Photosensitive resin composition SUMITOMO CHEMICAL CO (JP) 2003-08-13 CN disclosed
CN-1067683-C Substituted morpholine derivatives and their use as therapeutic agents MERK SHARP & DOHME LTD (GB) 2001-06-27 CN disclosed
CN-1139927-A Substituted morpholine derivatives and their use as therapeutic agents MERK SHARP & DOHME LTD (GB) 1997-01-08 CN disclosed
JP-H01216941-A PRODUCTION OF DIARYLMETHANE COMPOUND FUJI PHOTO FILM CO LTD 1989-08-30 JP disclosed
US-4797504-A HYDROXYLAMINES AND PHENYLENEDIAMINE DERIVATIVES BETZ LABORATORIES, INC. (US) 1989-01-10 US disclosed
EP-0266906-A2 Method and composition for inhibiting acrylate ester polymerization BETZ EUROPE, INC. (US) 1988-05-11 EP disclosed