Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055071 | 0.78 | ASAH1 (0.41) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4049543 | 0.78 | ASAH1 (0.41) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4052383 | 0.78 | ASAH1 (0.41) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL13754063 | 0.77 | ALDH1A1 (0.40) | ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL4051324 | 0.76 | ASAH1 (0.40) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL28013121 | 0.76 | LMNA (0.42) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL13754072 | 0.75 | HDAC7 (0.44) | ALDH1A1NPSR1 | |
| SCHEMBL15880443 | 0.74 | ASAH1 (0.49) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL15880312 | 0.72 | ASAH1 (0.47) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL13754074 | 0.72 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027752-A1 | CATALYTIC REACTIONS INVOLVING ALKENES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-03-08 | — | — | WO | disclosed |