Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055071 | 1.00 | ASAH1 (0.41) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4052383 | 1.00 | ASAH1 (0.41) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4051324 | 0.99 | ASAH1 (0.40) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4051018 | 0.84 | ALDH1A1 (0.48) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4057730 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5317773 | 0.78 | ASAH1 (0.40) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4057265 | 0.78 | NAAA (0.54) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4058970 | 0.78 | NAAA (0.54) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4364762 | 0.78 | NAAA (0.54) | ASAH1ALDH1A1ACER2CES2CES1 | |
| SCHEMBL4052380 | 0.71 | NPC1 (0.40) | ASAH1ALDH1A1ACER2CES1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |