Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9632054 | 0.98 | LMNA (0.51) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL9632837 | 0.94 | LMNA (0.50) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| SCHEMBL142264 | 0.91 | KDM4E (0.62) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL7473440 | 0.89 | LMNA (0.62) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| SCHEMBL6039195 | 0.88 | CA2 (0.53) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| SCHEMBL10415138 | 0.87 | CA2 (0.54) | PKMCYP1A2CYP3A4CA12CA1 | |
| SCHEMBL10639502 | 0.84 | PKM (0.53) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| SCHEMBL1803675 | 0.84 | PKM (0.56) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| SCHEMBL10864729 | 0.84 | PKM (0.47) | TSHRPKMCYP1A2CYP3A4NFKB1 | |
| SCHEMBL28732677 | 0.84 | PKM (0.55) | TSHRPKMCYP1A2CYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086074-A2 | A PROCESS FOR THE PREPARATION OF R (-) TAMSULOSIN HYDROCHLORIDE | USV LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |