SCHEMBL531797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL532856	0.89	ALDH1A1 (0.56)	ALDH1A1LMNAKMT2AMEN1MAPT
	SCHEMBL27732122	0.87	POLB (0.58)	POLBALDH1A1LMNAKMT2AMEN1
	SCHEMBL2698554	0.86	KMT2A (0.61)	POLBALDH1A1LMNAKMT2AMEN1
	SCHEMBL4173816	0.83	MAPT (0.51)	POLBALDH1A1LMNAKMT2AMEN1
	SCHEMBL10504393	0.83	PTGS2 (0.54)	POLBALDH1A1LMNAKMT2AMEN1
	SCHEMBL2339687	0.83	POLB (0.73)	POLBALDH1A1LMNAKMT2AMEN1
	SCHEMBL6708261	0.82	MEN1 (0.47)	ALDH1A1LMNAKMT2AMEN1MAPT
	SCHEMBL4180130	0.82	MAPT (0.51)	POLBALDH1A1LMNAKMT2AMEN1
	SCHEMBL16388497	0.82	ALDH1A1 (0.52)	ALDH1A1KMT2AMEN1MAPTL3MBTL1
	SCHEMBL13981920	0.82	MEN1 (0.47)	ALDH1A1LMNAKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.