Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320369 | 0.90 | NR1H2 (0.43) | PDE5APTGER1NR1H2NR1H3GUCY1A1 | |
| SCHEMBL2889462 | 0.84 | CYP1A2 (0.43) | PDE5ABUB1POLB | |
| SCHEMBL5321077 | 0.84 | NR1H2 (0.42) | PDE5APTGER1NR1H2NR1H3SLC22A12 | |
| SCHEMBL5317498 | 0.83 | CCR2 (0.36) | CCR2NR1H2NR1H3SLC22A12HTT | |
| SCHEMBL5318688 | 0.79 | AKR1B1 (0.36) | CCR2NR1H2NR1H3SLC22A12PTGDR2 | |
| SCHEMBL4097771 | 0.75 | CYP1A2 (0.54) | CCR2PTGER1SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL5270492 | 0.75 | AKR1B1 (0.39) | CCR2PTGER1NR1H2NR1H3SLC22A12 | |
| SCHEMBL5322124 | 0.74 | AKR1B1 (0.54) | SLC22A12PTGDR2AKR1B1 | |
| SCHEMBL5322328 | 0.74 | ENPP2 (0.41) | CCR2PTGER1NR1H2NR1H3SLC22A12 | |
| SCHEMBL5318544 | 0.74 | AKR1B1 (0.38) | CCR2PTGER1NR1H2NR1H3SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |