Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320143 | 0.84 | CCR2 (0.71) | CCR2 | |
| SCHEMBL5946854 | 0.82 | CCR2 (1.00) | CCR2 | |
| SCHEMBL5318250 | 0.82 | CCR2 (1.00) | CCR2 | |
| SCHEMBL5328493 | 0.79 | CCR2 (0.54) | CCR2 | |
| SCHEMBL5349966 | 0.79 | CCR2 (0.47) | CCR2 | |
| SCHEMBL5317370 | 0.78 | CCR2 (0.55) | CCR2 | |
| SCHEMBL5947196 | 0.77 | CCR2 (0.88) | CCR2 | |
| SCHEMBL5947191 | 0.77 | CCR2 (0.88) | CCR2 | |
| SCHEMBL5947254 | 0.75 | CCR2 (1.00) | CCR2 | |
| SCHEMBL5947029 | 0.75 | CCR2 (1.00) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802602-A1 | SUBSTITUTED DIPIPERDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006036527-A1 | SUBSTITUTED DIPIPERDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-04-06 | — | — | WO | disclosed |