Acetophenone

Acetophenone

SCHEMBL5318332

CC(=O)c1ccccc1.Cc1cc(C)c(C(=O)P(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
FFAR4 Q5NUL3 1/20 0.39
RAB9A P51151 3/20 0.38
KMT2A Q03164 5/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 3/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
POLB P06746 1/20 0.35
NPC1 O15118 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
BCL2L1 Q07817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130533 0.91 LMNA (0.38) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
Water SCHEMBL27425168 0.89 LMNA (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
Lithium SCHEMBL30025587 0.89 LMNA (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
SCHEMBL7640615 0.89 LMNA (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
Methyl Alcohol SCHEMBL28456191 0.89 LMNA (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
Hydrochloric Acid SCHEMBL7531737 0.89 LMNA (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
SCHEMBL7640621 0.87 KDM4E (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A
Benzophenone SCHEMBL28285683 0.85 ALDH1A1 (0.46) MAPTSMN1; SMN2RAB9AKMT2ALMNA
SCHEMBL9352643 0.83 LMNA (0.36) MAPTRAB9AKMT2ALMNAMEN1
SCHEMBL18963385 0.83 METAP2 (0.37) MAPTSMN1; SMN2FFAR4RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007134224-A2 DEVICES AND METHODS OF USE FOR TREATMENT OF SKIN AND HAIR LIVING PROOF, INC. (US) 2007-11-22 WO disclosed