Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875694 | 0.76 | ADRB1 (0.58) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL6833323 | 0.74 | ADRB1 (0.69) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7930799 | 0.73 | LMNA (0.63) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL9579153 | 0.72 | ADRB1 (0.72) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL7289414 | 0.71 | ADRB1 (0.60) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL5712379 | 0.70 | ADRB2 (0.49) | ADRB1CYP2D6ADRB2SIGMAR1 | |
| SCHEMBL11321065 | 0.69 | ADRB1 (0.46) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL13953857 | 0.69 | LMNA (0.57) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL17510375 | 0.69 | ADRB1 (0.67) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL1422064 | 0.68 | ADRB1 (0.49) | ADRB1LMNACYP2D6MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087367-A9 | METHODS AND COMPOSITIONS FOR MODULATING THE MOBILIZATION OF STEM CELLS | SINAI SCHOOL MEDICINE (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007087367-A2 | METHODS AND COMPOSITIONS FOR MODULATING THE MOBILIZATION OF STEM CELLS | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2007-08-02 | — | — | WO | disclosed |
| WO-2004058170-A2 | METHODS FOR TREATING MALARIA BY MODULATION OF G PROTEIN FUNCTION | NORTHWESTERN UNIVERSITY (US) | 2004-07-15 | — | — | WO | disclosed |