Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913867 | 0.85 | MAPT (0.42) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5316830 | 0.84 | KMT2A (0.35) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5314454 | 0.83 | TRPA1 (0.33) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5311615 | 0.83 | TRPA1 (0.44) | KMT2ARAB9ASMN1; SMN2KDM4ETRPA1 | |
| SCHEMBL9068576 | 0.82 | MAPT (0.42) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5314610 | 0.80 | POLB (0.40) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5312106 | 0.80 | TRPA1 (0.35) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5314175 | 0.80 | ATM (0.40) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5310925 | 0.79 | MEN1 (0.37) | MAPTMEN1USP2ALOX15KMT2A | |
| SCHEMBL5316118 | 0.79 | KMT2A (0.37) | MEN1KMT2ARAB9AALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |