Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | IL2 | P60568 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314994 | 0.86 | TLR8 (0.44) | KDM4ETLR7TLR8KMT2A | |
| SCHEMBL5314610 | 0.84 | POLB (0.40) | CYP1A2HPGDRAB9AGAAKMT2A | |
| SCHEMBL5312106 | 0.84 | TRPA1 (0.35) | TRPA1CYP1A2TLR7TLR8RAB9A | |
| SCHEMBL5316118 | 0.83 | KMT2A (0.37) | TRPA1CYP1A2RAB9AKMT2A | |
| SCHEMBL5313998 | 0.83 | RAB9A (0.36) | TRPA1CYP1A2KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5318477 | 0.83 | MAPT (0.39) | TRPA1KDM4ETLR7TLR8SMN1; SMN2 | |
| SCHEMBL5314713 | 0.83 | TRPA1 (0.34) | TRPA1CYP1A2RAB9AKMT2A | |
| SCHEMBL5311213 | 0.83 | RAB9A (0.35) | TRPA1CYP1A2SMN1; SMN2RAB9AGAA | |
| SCHEMBL4908707 | 0.82 | IL2 (0.44) | TRPA1CYP1A2IL2TLR7TLR8 | |
| SCHEMBL5312164 | 0.81 | TRPA1 (0.33) | TRPA1CYP1A2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |