Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068576 | 0.86 | MAPT (0.42) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL4909640 | 0.85 | TLR7 (0.43) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL5318477 | 0.85 | MAPT (0.39) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL4915675 | 0.81 | TLR7 (0.38) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL4150636 | 0.81 | KMT2A (0.36) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL4145038 | 0.80 | ATM (0.35) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL4908707 | 0.79 | IL2 (0.44) | TLR7TRPV1TLR8ALDH1A1TRPA1 | |
| SCHEMBL4142017 | 0.78 | TRPA1 (0.33) | MAPTMEN1KMT2AUSP2ALOX15 | |
| SCHEMBL13774520 | 0.78 | MEN1 (0.41) | MEN1KMT2ARAB9ATRPA1POLB | |
| SCHEMBL14546151 | 0.77 | KMT2A (0.34) | MAPTMEN1KMT2AUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-13 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274884-A1 | Novel use of (N'-methyl)benzoylurea compound | RNGTT, L3MBTL4, MYB | MAPT 4076/4885MEN1 1701/4885KMT2A 389/4885 |
| US-20080280988-A1 | Use of (N'-Methyl) benzoylurea compound | L3MBTL4, L3MBTL3, L3MBTL1 | MAPT 4470/4885MEN1 1282/4885KMT2A 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.