SCHEMBL5318547

SCHEMBL5318547

CC(C)c1ccc2cnncc2c1.c1ccc2c(-c3nncc4ccccc34)cccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 4/20 0.46
ALDH1A1 P00352 3/20 0.38
CRHR1 P34998 1/20 0.36
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
UGT2B7 P16662 1/20 0.35
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
SOS1 Q07889 1/20 0.34
SLC22A12 Q96S37 1/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
GPR35 Q9HC97 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27517833 0.91 KDR (0.48) KDRALDH1A1CRHR1MAPTHPGD
SCHEMBL30632058 0.81 SMN1; SMN2 (0.47) KDRALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL2228819 0.81 SMN1; SMN2 (0.47) KDRALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL2230006 0.74 UGT2B7 (0.42) ALDH1A1MAPTSMN1; SMN2UGT2B7ADRA2A
SCHEMBL29941671 0.69 MAPK14 (0.48) KDRALDH1A1MAPTSMN1; SMN2MAPK14
SCHEMBL9179432 0.68 UGT2B7 (0.44) ALDH1A1CRHR1MAPTHPGDSMN1; SMN2
SCHEMBL598202 0.68 AKR1B1 (0.54) ALDH1A1MAPTHPGDUGT2B7AKR1B1
SCHEMBL30523852 0.67 KDM4E (0.55) KDRALDH1A1MAPTSMN1; SMN2GRM5
SCHEMBL1673296 0.67 KDM4E (0.55) KDRALDH1A1MAPTSMN1; SMN2GRM5
SCHEMBL3884938 0.66 ALDH1A1 (0.39) ALDH1A1MAPTHPGDSMN1; SMN2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262000-B2 Photothermographic material and image forming method for the photothermographic material FUJIFILM CORPORATION (JP) 2007-08-28 US disclosed
EP-1441254-B1 Photothermographic material FUJIFILM CORP (JP) 2007-03-28 EP disclosed
EP-1742105-A2 Photothermographic material Fuji Photo Film Co., Ltd. (JP) 2007-01-10 EP disclosed
US-20060110691-A9 Photothermographic material OHZEKI TOMOYUKI 2006-05-25 US disclosed
US-20040234906-A1 high sensitivity with a low degree of fogging and is excellent in raw stock storability and print-out resistance of images; contains: a compound having an adsorption group to silver halide and a reducing group, or a precursor of the compound; and a development accelerator FUJIFILM CORPORATION (JP) 2004-11-25 US disclosed
EP-1441254-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2004-07-28 EP disclosed
US-20040081926-A1 Photothermographic material and image forming method for the photothermographic material FUJIFILM CORPORATION (JP) 2004-04-29 US disclosed