Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | GOT1 | P17174 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.55 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523852 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL13911023 | 0.91 | KDM4E (0.52) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL4499780 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL1268508 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL29816494 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL28657632 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL28073282 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL2228819 | 0.83 | SMN1; SMN2 (0.47) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL30632058 | 0.83 | SMN1; SMN2 (0.47) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL5146230 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12171665-B2 | Compression resistant implants including an oxysterol and methods of use | WARSAW ORTHOPEDIC, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| US-12171909-B2 | Implants having a drug load of an oxysterol and methods of use | WARSAW ORTHOPEDIC, INC. (US) | 2024-12-24 | — | — | US | disclosed |
| US-20230166003-A1 | IMPLANTS HAVING A DRUG LOAD OF AN OXYSTEROL AND METHODS OF USE | WARSAW ORTHOPEDIC, INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-11464888-B2 | Moldable formulations containing an oxysterol in an acellular tissue matrix | WARSAW ORTHOPEDIC, INC. (US) | 2022-10-11 | — | — | US | disclosed |
| EP-3617217-B1 | PROCESS FOR THE PRODUCTION OF OXYSTEROLS | WARSAW ORTHOPEDIC INC (US) | 2022-09-07 | — | — | EP | disclosed |
| US-11384114-B2 | Polymorphic forms of an oxysterol and methods of making them | WARSAW ORTHOPEDIC, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| EP-3827833-B1 | METHODS FOR THE SEPARATION AND DETECTION OF AN OXYSTEROL | WARSAW ORTHOPEDIC INC (US) | 2022-06-15 | — | — | EP | disclosed |
| US-11324759-B2 | Oxysterol-statin compounds for bone growth | WARSAW ORTHOPEDIC, INC. (US) | 2022-05-10 | — | — | US | disclosed |
| EP-3323437-B1 | LYOPHILIZED MOLDABLE IMPLANTS CONTAINING AN OXYSTEROL | WARSAW ORTHOPEDIC INC (US) | 2022-04-27 | — | — | EP | disclosed |
| EP-3367973-B1 | IMPLANTS HAVING A DRUG LOAD OF AN OXYSTEROL AND METHODS OF USE | WARSAW ORTHOPEDIC INC (US) | 2022-03-23 | — | — | EP | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| EP-1317464-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | Applera Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | APPLERA CORPORATION (US) | 2003-03-20 | — | — | US | disclosed |
| US-20020102590-A1 | Fluorescent nucleobase conjugates having anionic linkers | PE CORPORATION (NY) (US) | 2002-08-01 | — | — | US | disclosed |
| WO-2002030944-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | APPLERA CORPORATION (US) | 2002-04-18 | — | — | WO | disclosed |
| US-6372907-B1 | LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING | APPTERA CORPORATION | 2002-04-16 | — | — | US | disclosed |
| EP-1141137-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | Applera Corporation (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001032783-A1 | WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF | APPLERA CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6191278-B1 | COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS | PE CORPORATION | 2001-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12171909-B2 | Implants having a drug load of an oxysterol and methods of use | SOST, CYP17A1, HSD17B7 | KDM4E 416/4885ALDH1A1 2822/4885LMNA 1681/4885 |
| US-20230166003-A1 | IMPLANTS HAVING A DRUG LOAD OF AN OXYSTEROL AND METHODS OF USE | SOST, CYP17A1, HSD17B7 | KDM4E 416/4885ALDH1A1 2822/4885LMNA 1681/4885 |
| US-11324759-B2 | Oxysterol-statin compounds for bone growth | HMGCR, SOST, OSBP2 | KDM4E 3571/4885ALDH1A1 1912/4885LMNA 3608/4885 |
| US-11384114-B2 | Polymorphic forms of an oxysterol and methods of making them | HSD3B1, VKORC1L1, VKORC1 | KDM4E 4551/4885ALDH1A1 1855/4885LMNA 874/4885 |
| US-20030055257-A1 | Water-soluble rhodamine dye conjugates | SLC43A3, ABCG2, TARBP1 | KDM4E 4494/4885ALDH1A1 1349/4885LMNA 2551/4885 |
| US-20020102590-A1 | Fluorescent nucleobase conjugates having anionic linkers | DNTT, DUT, NT5C3B | KDM4E 1295/4885ALDH1A1 2642/4885LMNA 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.