SCHEMBL5318682 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KDM2B	Q8NHM5	9/20	0.49

▸	POLB	P06746	1/20	0.47

▸	MEN1	O00255	2/20	0.44

▸	KMT2A	Q03164	2/20	0.44

▸	ALDH1A1	P00352	2/20	0.44

▸	GAA	P10253	2/20	0.44

▸	L3MBTL1	Q9Y468	2/20	0.41

▸	KDM4E	B2RXH2	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	TDP1	Q9NUW8	1/20	0.40

▸	PDE2A	O00408	1/20	0.40

▸	NPC1	O15118	1/20	0.39

▸	HSD11B1	P28845	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL970360	0.81	POLB (0.51)	KDM2BPOLBMEN1KMT2AALDH1A1
SCHEMBL970359	0.81	POLB (0.51)	KDM2BPOLBMEN1KMT2AALDH1A1
SCHEMBL4755206	0.80	POLB (0.52)	KDM2BPOLBMEN1KMT2AALDH1A1
SCHEMBL5592323	0.79	POLB (0.42)	KDM2BPOLBMEN1KMT2AALDH1A1
SCHEMBL26599052	0.78	KDM2B (0.46)	KDM2BPOLBKMT2AGAATSHR
SCHEMBL30606587	0.78	KDM2B (0.46)	KDM2BPOLBKMT2AGAATSHR
SCHEMBL5593253	0.78	KDM2B (0.43)	KDM2BPOLBMEN1KMT2AALDH1A1
SCHEMBL4975598	0.77	MEN1 (0.53)	KDM2BMEN1KMT2AALDH1A1KDM4E
SCHEMBL3965621	0.77	KDM2B (0.66)	KDM2BPOLBMEN1KMT2AALDH1A1
SCHEMBL5593263	0.76	GRM5 (0.39)	KDM2BMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007117557-A2	DIAMINOPROPANOL RENIN INHIBITORS	VITAE PHARMACEUTICALS, INC. (US)	2007-10-18	—	—	WO	disclosed