SCHEMBL5593263 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GRM5	P41594	4/20	0.39

▸	REN	P00797	3/20	0.39

▸	GAA	P10253	2/20	0.38

▸	RAB9A	P51151	1/20	0.38

▸	KDM2B	Q8NHM5	1/20	0.38

▸	ALDH1A1	P00352	3/20	0.37

▸	MEN1	O00255	3/20	0.37

▸	KMT2A	Q03164	3/20	0.37

▸	L3MBTL1	Q9Y468	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5592323	0.89	POLB (0.42)	GRM5RENGAAKDM2BALDH1A1
SCHEMBL3571520	0.84	KAT6A (0.46)	RENGAARAB9AALDH1A1MEN1
SCHEMBL3565628	0.84	KAT6A (0.46)	RENGAARAB9AALDH1A1MEN1
SCHEMBL3885007	0.79	GAA (0.38)	GAARAB9AKDM2BALDH1A1MEN1
SCHEMBL5318682	0.76	KDM2B (0.49)	GAARAB9AKDM2BALDH1A1MEN1
SCHEMBL5593533	0.76	REN (0.42)	GRM5RENL3MBTL1
SCHEMBL5593253	0.73	KDM2B (0.43)	GAARAB9AKDM2BALDH1A1MEN1
SCHEMBL2847273	0.73	POLB (0.47)	GRM5KDM2BALDH1A1MEN1KMT2A
SCHEMBL2850274	0.73	KAT6A (0.49)	RENALDH1A1MEN1KMT2A
SCHEMBL2850273	0.73	KAT6A (0.49)	RENALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007117560-A2	PIPERIDINE AND MORPHOLINE RENIN INHIBITORS	VITAE PHARMACEUTICALS, INC. (US)	2007-10-18	—	—	WO	disclosed