Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434445 | 0.94 | POLB (0.51) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT | |
| SCHEMBL14434469 | 0.93 | POLB (0.50) | ALDH1A1POLBPABPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14435097 | 0.93 | POLB (0.50) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT | |
| SCHEMBL14434447 | 0.92 | POLB (0.49) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT | |
| SCHEMBL14434451 | 0.92 | POLB (0.51) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT | |
| SCHEMBL14435090 | 0.91 | PABPC1 (0.49) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT | |
| SCHEMBL5318260 | 0.91 | POLB (0.48) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT | |
| SCHEMBL5342566 | 0.90 | POLB (0.47) | ALDH1A1POLBPABPC1SMN1; SMN2KMT2A | |
| SCHEMBL14434072 | 0.89 | ALDH1A1 (0.47) | ALDH1A1POLBPABPC1MAPTHTT | |
| SCHEMBL14434452 | 0.89 | POLB (0.48) | ALDH1A1POLBPABPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | claimed |
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |