Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318868 | 0.92 | ALDH1A1 (0.51) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14434445 | 0.92 | POLB (0.51) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14435097 | 0.91 | POLB (0.50) | POLBALDH1A1PABPC1SMN1; SMN2LMNA | |
| SCHEMBL14434469 | 0.91 | POLB (0.50) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14434499 | 0.91 | POLB (0.42) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14434452 | 0.91 | POLB (0.48) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14434472 | 0.91 | CXCR2 (0.50) | POLBPABPC1GFERCXCR2MEN1 | |
| SCHEMBL14434876 | 0.90 | CASP6 (0.41) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14434441 | 0.90 | POLB (0.44) | POLBCASP6ALDH1A1PABPC1SMN1; SMN2 | |
| SCHEMBL14434447 | 0.90 | POLB (0.49) | POLBALDH1A1PABPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |