Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.42 |
| ▸ | GABRE | P78334 | 4/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26096395 | 0.88 | AHR (0.53) | AHRPTPN1ERN1TDP1 | |
| SCHEMBL787917 | 0.80 | MAOA (0.44) | AHRPTPN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2287518 | 0.78 | AHR (0.64) | AHRALDH1A1LMNAKMT2AGPR55 | |
| SCHEMBL22511380 | 0.78 | TTR (0.54) | PTPN1ALDH1A1KMT2AERN1TDP1 | |
| SCHEMBL14476377 | 0.76 | AHR (0.53) | AHRALDH1A1LMNAKMT2AGPR55 | |
| SCHEMBL18878911 | 0.76 | PTPN1 (0.56) | AHRPTPN1KMT2AGABRPGABRD | |
| SCHEMBL18267698 | 0.76 | ALOX5 (0.51) | AHRPTPN1GABRPGABRDGABRA1 | |
| SCHEMBL21191630 | 0.76 | AHR (0.56) | AHRALDH1A1LMNAKMT2AGPR55 | |
| SCHEMBL2958772 | 0.76 | AHR (0.56) | AHRALDH1A1LMNAKMT2AGPR55 | |
| SCHEMBL20754180 | 0.76 | AHR (0.56) | AHRALDH1A1LMNAKMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095495-A2 | BENZODIAZEPINE GCNF MODULATORS FOR STEM CELL MODULATION | PHARMACOPEIA, INC. (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007095495-A2 | BENZODIAZEPINE GCNF MODULATORS FOR STEM CELL MODULATION | PHARMACOPEIA, INC. (US) | 2007-08-23 | — | — | WO | disclosed |