SCHEMBL787917

SCHEMBL787917

O=Cc1cccc2c1oc1ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.44
THRB P10828 2/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
BLM P54132 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PTPN1 P18031 1/20 0.44
MAOB P27338 1/20 0.44
ALOX5 P09917 3/20 0.43
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
GLA P06280 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
PGAM1 P18669 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13630709 0.87 MAOA (0.60) MAOATHRBLMNAPTPN1MAOB
SCHEMBL19398804 0.86 ALOX5 (0.53) MAOATHRBLMNAMEN1KMT2A
SCHEMBL9779012 0.81 AHR (0.46) MAOATHRBMEN1KMT2APTPN1
SCHEMBL1420857 0.81 ALOX5 (0.45) MAOALMNAMEN1KMT2AALOX5
SCHEMBL17196520 0.81 ALOX5 (0.42) MAOATHRBLMNAMEN1KMT2A
SCHEMBL23348910 0.80 KMT2A (0.46) MAOALMNAMEN1KMT2APTPN1
SCHEMBL30661436 0.80 ERN1 (0.42) MAOAPTPN1MAOBALDH1A1TRIM24
SCHEMBL5319348 0.80 AHR (0.51) LMNAKMT2ATDP1PTPN1ALDH1A1
SCHEMBL19774245 0.79 KDM4E (0.45) MAOATHRBMEN1KMT2APTPN1
SCHEMBL8536418 0.79 ESR2 (0.41) MAOATHRBMEN1KMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119025-A Thioketone metal surface corrosion inhibitor material, effect verification method and application 北京理工大学 2024-12-13 CN claimed
CN-118994138-A Preparation method of thioketone metal surface corrosion inhibitor 北京理工大学 2024-11-22 CN claimed
CN-118546103-A 4-Formamide oxazole compound and preparation method and application thereof 上海大学 2024-08-27 CN claimed
US-12577263-B2 Compound and optical film comprising same LG CHEM, LTD. (KR) 2026-03-17 US disclosed
US-20260040813-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-05 US disclosed
US-12495715-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-12-09 US disclosed
US-12187748-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-01-07 US disclosed
CN-119119025-A Thioketone metal surface corrosion inhibitor material, effect verification method and application 北京理工大学 2024-12-13 CN disclosed
CN-118994138-A Preparation method of thioketone metal surface corrosion inhibitor 北京理工大学 2024-11-22 CN disclosed
CN-118546103-A 4-Formamide oxazole compound and preparation method and application thereof 上海大学 2024-08-27 CN disclosed
US-20240254087-A1 SELECTIVE, PARTIAL, AND ARRESTIN-BIASED 5-HT2A AGONISTS WITH UTILITY IN VARIOUS DISORDERS NATIONAL INSTITUTES OF HEALTH 2024-08-01 US disclosed
US-20130181190-A1 NOVEL HETEROLEPTIC IRIDIUM COMPLEXE UNIVERSAL DISPLAY CORPORATION (US) 2013-07-18 US disclosed
US-20130181190-A1 NOVEL HETEROLEPTIC IRIDIUM COMPLEXE UNIVERSAL DISPLAY CORPORATION (US) 2013-07-18 US disclosed
US-20130023541-A1 VOLTAGE-GATED SODIUM CHANNEL BLOCKERS GLAXO GROUP LIMITED 2013-01-24 US disclosed
US-20130023541-A1 VOLTAGE-GATED SODIUM CHANNEL BLOCKERS GLAXO GROUP LIMITED 2013-01-24 US disclosed
US-20120071487-A1 PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE ATIR HOLDING S.A. 2012-03-22 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
WO-2010137018-A1 PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE ATIR HOLDING S.A. (LU) 2010-12-02 WO disclosed
US-4344956-A Oxotetrahydrothiophenes ERCOLI NICOLO 1982-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 MAOA 42/4885THRB 2485/4885LMNA 625/4885
US-20130181190-A1 NOVEL HETEROLEPTIC IRIDIUM COMPLEXE OCIAD1, OCIAD2, BRD1 MAOA 1702/4885THRB 4193/4885LMNA 4875/4885
US-12495715-B2 Organic electroluminescent materials and devices MCOLN2, MCOLN1, MCOLN3 MAOA 261/4885THRB 2370/4885LMNA 39/4885
US-20130023541-A1 VOLTAGE-GATED SODIUM CHANNEL BLOCKERS KCNB1, KCNB2, SCNN1B MAOA 1655/4885THRB 1071/4885LMNA 611/4885
US-20260040813-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, MSRB3, GSR MAOA 1432/4885THRB 1242/4885LMNA 125/4885
US-12187748-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, TRPA1 MAOA 596/4885THRB 1722/4885LMNA 2303/4885
US-20120071487-A1 PIPERAZINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE DPYD, BRPF3, BRPF1 MAOA 2827/4885THRB 2336/4885LMNA 4686/4885
US-12577263-B2 Compound and optical film comprising same NR2E3, CBR1, CBR3 MAOA 208/4885THRB 1917/4885LMNA 3141/4885
US-20240254087-A1 SELECTIVE, PARTIAL, AND ARRESTIN-BIASED 5-HT2A AGONISTS WITH UTILITY IN VARIOUS DISORDERS HTR2A, HTR5A, HTR1A MAOA 188/4885THRB 211/4885LMNA 3342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.