Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 6/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.42 |
| ▸ | GCLC | P48506 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325110 | 0.87 | KMT2A (0.50) | KMT2APMP22ALOX15BLMSLC1A2 | |
| SCHEMBL5326654 | 0.85 | GRIK1 (0.56) | KMT2APMP22ALOX15BLMSLC1A2 | |
| SCHEMBL4008043 | 0.84 | CHRM1 (0.40) | KMT2ASLC1A2SLC1A1SLC1A3GRIK1 | |
| Asparagine SCHEMBL20547283 | 0.82 | GRIK1 (0.57) | KMT2APMP22ALOX15BLMSLC1A2 | |
| SCHEMBL9104581 | 0.80 | CHRM1 (0.40) | KMT2ASLC1A2SLC1A1SLC1A3GRIK1 | |
| Norvaline SCHEMBL840389 | 0.77 | SLC1A2 (0.64) | KMT2APMP22ALOX15BLMSLC1A2 | |
| Norvaline SCHEMBL38404 | 0.77 | — | — | |
| Norvaline SCHEMBL21114359 | 0.77 | SLC1A2 (0.64) | KMT2APMP22ALOX15BLMSLC1A2 | |
| Norvaline SCHEMBL17449755 | 0.77 | — | — | |
| Norvaline SCHEMBL197812 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | KMT2A 3586/4885PMP22 990/4885ALOX15 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.