Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104581 | 0.95 | CHRM1 (0.40) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL19847385 | 0.91 | CA2 (0.47) | TDP1CYP3A4TSHRCA1CA2 | |
| SCHEMBL7895720 | 0.90 | CA2 (0.40) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL5739281 | 0.89 | LMNA (0.45) | CA1CA2GRIK1SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6432498 | 0.89 | CA2 (0.45) | TDP1CYP3A4TSHRCA1CA2 | |
| SCHEMBL28331224 | 0.88 | LMNA (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL19412264 | 0.87 | LMNA (0.48) | CYP3A4CA2GRIK1GRIK2GPR84 | |
| SCHEMBL29968887 | 0.87 | LMNA (0.48) | CYP3A4CA2GRIK1GRIK2GPR84 | |
| SCHEMBL20835160 | 0.87 | LMNA (0.48) | CYP3A4CA2GRIK1GRIK2GPR84 | |
| SCHEMBL21894626 | 0.86 | CACNA2D1 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | claimed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | claimed |
| CN-114340734-A | Novel compounds and methods | 博善人工智能生物科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3959765-A1 | POLYVINYL PYROLLIDONE AS A DISPERSANT FOR LITHIUM ION BATTERY CATHODE PRODUCTION | Dow Global Technologies LLC (US) | 2022-03-02 | — | — | EP | disclosed |
| US-10941166-B2 | Crystalline high degree of condensation titanium-based inorganic-organic hybrid solid MOF material, method for preparing same and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-03-09 | — | — | US | disclosed |
| US-20190248814-A1 | CRYSTALLINE HIGH DEGREE OF CONDENSATION TITANIUM-BASED INORGANIC-ORGANIC HYBRID SOLID MOF MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-08-15 | — | — | US | disclosed |
| WO-2017211923-A1 | CRYSTALLINE HIGH DEGREE OF CONDENSATION TITANIUM-BASED INORGANIC-ORGANIC HYBRID SOLID MOF MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-12-14 | — | — | WO | disclosed |
| CN-102459416-B | Process for production of polyhydroxyimide | NISSAN CHEMICAL IND LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-101535285-B | Novel benzofuran type derivatives, a composition comprising the same for treating or preventing cognitive dysfunction and the use thereof | DIGITAL BIOTECH CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-102459416-A | Method for producing polyhydroxyimide | NISSAN CHEMICAL IND LTD | 2012-05-16 | — | — | CN | disclosed |
| WO-2009131196-A1 | SUBSTITUTED PYRROLIDINE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-29 | — | — | WO | disclosed |
| EP-1931471-A1 | IMPROVED CATALYST SYSTEM | Lucite International UK Limited (GB) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |
| US-20070254898-A1 | Thienopyrimidine and Thienopyridine Derivatives Substituted with Cyclic Amino Group | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| WO-2007020379-A1 | IMPROVED CATALYST SYSTEM | LUCITE INTERNATIONAL UK LIMITED (GB) | 2007-02-22 | — | — | WO | disclosed |
| US-6840967-B1 | Dye diffusion promoting agents for aramids | SOUTHERN MILLS, INC. (US) | 2005-01-11 | — | — | US | disclosed |
| US-5306312-A | Dyeing fabric by heating in solution containing dye and aliphatic amide dye diffusion promoter | BURLINGTON INDUSTRIES, INC. (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0349786-B1 | METHOD OF STABILIZING 3-ISOTHIAZOLONE SOLUTION | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| EP-0349786-A1 | Method of stabilizing 3-isothiazolone solution | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4246282-A | ω-Dialkylalkanoic acid derivatives used to induce antianoxic activity | LABAZ (FR) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254898-A1 | Thienopyrimidine and Thienopyridine Derivatives Substituted with Cyclic Amino Group | HRH2, HRH3, HRH4 | CHRM1 732/4885AKR1A1 2832/4885CHRM3 2532/4885 |
| US-10941166-B2 | Crystalline high degree of condensation titanium-based inorganic-organic hybrid solid MOF material, method for preparing same and uses thereof | TPR, SPOP, POF1B | CHRM1 1628/4885AKR1A1 4690/4885CHRM3 2093/4885 |
| US-20190248814-A1 | CRYSTALLINE HIGH DEGREE OF CONDENSATION TITANIUM-BASED INORGANIC-ORGANIC HYBRID SOLID MOF MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF | TPR, SPOP, POF1B | CHRM1 1628/4885AKR1A1 4690/4885CHRM3 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.