SCHEMBL5319700

SCHEMBL5319700

C=CC(=O)OCCCOc1ccc(C(=O)Oc2cccc(OC(=O)c3ccc(OCCCOC(=O)C=C)cc3)c2C)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
L3MBTL1 Q9Y468 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAPT P10636 3/20 0.43
KMT2A Q03164 3/20 0.43
TSHR P16473 2/20 0.42
HPGD P15428 1/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 2/20 0.42
HTT P42858 1/20 0.41
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
PRSS1 P07477 1/20 0.39
ACR P10323 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4326364 0.96 THRB (0.48) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL3225142 0.89 TDP1 (0.54) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL7571753 0.89 THRB (0.50) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL15523698 0.89 HTT (0.47) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL7268202 0.89 HTT (0.47) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL24379077 0.87 L3MBTL1 (0.54) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL16379468 0.87 THRB (0.45) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL7574204 0.87 THRB (0.50) THRBL3MBTL1TDP1MAPTKMT2A
SCHEMBL30636399 0.86 THRB (0.56) THRBL3MBTL1TDP1MAPTTSHR
SCHEMBL1979330 0.86 L3MBTL1 (0.46) THRBL3MBTL1TDP1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637618-B2 Method of manufacture of a resin MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-05-26 US claimed
US-20250136869-A1 ROBOTIC LIQUID CRYSTAL ELASTOMERS, APPARATUS, AND METHOD OF MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-05-01 US claimed
WO-2025090916-A1 ROBOTIC LIQUID CRYSTAL ELASTOMERS, APPARATUS, AND METHOD OF MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-05-01 WO claimed
US-12637618-B2 Method of manufacture of a resin MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-05-26 US disclosed
WO-2025090916-A1 ROBOTIC LIQUID CRYSTAL ELASTOMERS, APPARATUS, AND METHOD OF MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-05-01 WO disclosed
US-20250136869-A1 ROBOTIC LIQUID CRYSTAL ELASTOMERS, APPARATUS, AND METHOD OF MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-05-01 US disclosed
US-20200239774-A1 ALIGNED NEMATIC ELASTOMER UNIVERSITY OF LEEDS (GB) 2020-07-30 US disclosed
CN-111247229-A Aligned nematic elastomers 利兹大学 2020-06-05 CN disclosed
WO-2007072426-A2 METHOD OF MANUFACTURING A POLARIZATION RETARDATION FILM KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637618-B2 Method of manufacture of a resin LCT, KDM2A, LCP1 THRB 4464/4885L3MBTL1 1498/4885TDP1 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.