Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243927 | 1.00 | GRN (0.40) | GRNSORT1METAP2METAP1SLC1A3 | |
| SCHEMBL5319747 | 1.00 | GRN (0.40) | GRNSORT1METAP2METAP1SLC1A3 | |
| SCHEMBL19690672 | 0.86 | SLC1A3 (0.43) | GRNSORT1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4196009 | 0.83 | SLC1A3 (0.36) | GRNSORT1METAP2METAP1SLC1A3 | |
| SCHEMBL4196007 | 0.83 | SLC1A3 (0.36) | GRNSORT1METAP2METAP1SLC1A3 | |
| SCHEMBL28948924 | 0.79 | LTA4H (0.44) | GRNSORT1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21197392 | 0.79 | LTA4H (0.44) | GRNSORT1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7419744 | 0.79 | LTA4H (0.38) | GRNSORT1METAP2SLC1A3SLC1A2 | |
| SCHEMBL5848395 | 0.78 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5848443 | 0.78 | METAP2 (0.56) | METAP2METAP1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |