SCHEMBL5319993 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	DRD2	P14416	1/20	0.47

▸	ADRA1A	P35348	1/20	0.47

▸	MAPT	P10636	1/20	0.35

▸	HCRTR1	O43613	2/20	0.35

▸	HCRTR2	O43614	2/20	0.35

▸	MGLL	Q99685	1/20	0.35

▸	OGA	O60502	1/20	0.34

▸	LRRK2	Q5S007	1/20	0.33

▸	DRD4	P21917	1/20	0.33

▸	TMEM97	Q5BJF2	1/20	0.33

▸	SIGMAR1	Q99720	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5320289	0.94	DRD2 (0.40)	DRD2ADRA1AHCRTR1HCRTR2MGLL
SCHEMBL5322375	0.90	DRD2 (0.41)	DRD2ADRA1AMAPTOGALRRK2
SCHEMBL14396688	0.82	DRD2 (0.35)	DRD2ADRA1AMGLLOGADRD4
SCHEMBL5319996	0.82	DRD2 (0.52)	DRD2ADRA1AMAPTDRD4TMEM97
SCHEMBL5324511	0.80	DRD2 (0.49)	DRD2ADRA1AOGA
SCHEMBL5323016	0.79	DRD2 (0.46)	DRD2ADRA1AMAPT
SCHEMBL5324921	0.79	ALDH1A1 (0.41)	DRD2ADRA1AHCRTR1HCRTR2
SCHEMBL5394993	0.79	CHRM2 (0.47)	DRD2ADRA1AOGA
SCHEMBL5388493	0.78	DRD2 (0.40)	DRD2ADRA1AOGALRRK2
SCHEMBL5320284	0.78	DRD2 (0.46)	DRD2ADRA1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007114916-A2	ARYLBENZYLPIPERIDINE COMPOUNDS	H. LUNDBECK A/S (DK)	2007-10-11	—	—	WO	claimed
WO-2007114916-A2	ARYLBENZYLPIPERIDINE COMPOUNDS	H. LUNDBECK A/S (DK)	2007-10-11	—	—	WO	disclosed