SCHEMBL5320001

SCHEMBL5320001

CCCCOC(=O)CC(CN)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.55
GABBR1 Q9UBS5 2/20 0.55
ALDH1A1 P00352 3/20 0.49
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
LMNA P02545 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.44
F2 P00734 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
PKM P14618 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5321126 0.94 GABBR2 (0.53) GABBR2GABBR1ALDH1A1TSHRSMN1; SMN2
SCHEMBL5320904 0.91 GABBR2 (0.58) GABBR2GABBR1ALDH1A1TSHRSMN1; SMN2
SCHEMBL9467365 0.91 ALDH1A1 (0.54) ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2
SCHEMBL9468152 0.87 ALDH1A1 (0.50) GABBR2GABBR1ALDH1A1TSHRTDP1
SCHEMBL9467430 0.86 ALDH1A1 (0.59) ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2
SCHEMBL14680082 0.85 NPC1 (0.56) ALDH1A1TSHRSMN1; SMN2NPC1RAB9A
SCHEMBL5319563 0.85 GABBR2 (0.62) GABBR2GABBR1ALDH1A1TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL987303 0.84 GABBR2 (0.60) GABBR2GABBR1ALDH1A1TSHRSMN1; SMN2
SCHEMBL23191566 0.83 TSHR (0.53) ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2
SCHEMBL5720836 0.82 TSHR (0.49) ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007096314-A2 ENZYMATIC RESOLUTION OF RACEMIC 3-ARYL-4-AMINOBUTYRIC ACID VEINBERG GRIGORY (LV) 2007-08-30 WO claimed