Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 5/20 | 0.62 |
| ▸ | GABBR1 | Q9UBS5 | 5/20 | 0.62 |
| ▸ | F2 | P00734 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL987303 | 0.98 | GABBR2 (0.60) | GABBR2GABBR1F2ALDH1A1F10 | |
| SCHEMBL232194 | 0.90 | F2 (0.59) | GABBR2GABBR1F2ALDH1A1F10 | |
| SCHEMBL5320904 | 0.88 | GABBR2 (0.58) | GABBR2GABBR1F2ALDH1A1F10 | |
| Hydrochloric Acid SCHEMBL27921429 | 0.87 | GABBR2 (0.54) | GABBR2GABBR1F2ALDH1A1F10 | |
| SCHEMBL4405154 | 0.87 | F2 (0.56) | F2ALDH1A1F10TSHRCYP1A2 | |
| SCHEMBL30040482 | 0.87 | F2 (0.56) | F2ALDH1A1F10TSHRCYP1A2 | |
| SCHEMBL7141857 | 0.85 | F2 (0.55) | GABBR2GABBR1F2ALDH1A1F10 | |
| SCHEMBL28642234 | 0.85 | F2 (0.55) | GABBR2GABBR1F2ALDH1A1F10 | |
| SCHEMBL3863643 | 0.85 | F2 (0.55) | F2ALDH1A1F10TSHRCYP1A2 | |
| SCHEMBL5320001 | 0.85 | GABBR2 (0.55) | GABBR2GABBR1F2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103408480-A | 4-phenyl-pyrrolidone synthesis process | ZHANGJIAGANG WEISHENG BIOLOG PHARMACEUTICAL CO LTD | 2013-11-27 | — | — | CN | claimed |
| WO-2007096314-A2 | ENZYMATIC RESOLUTION OF RACEMIC 3-ARYL-4-AMINOBUTYRIC ACID | VEINBERG GRIGORY (LV) | 2007-08-30 | — | — | WO | claimed |
| EP-2456309-B1 | Azabicyclo[3.2.1]octyl derivatives for use in the treatment of HIV. | GLAXOSMITHKLINE LLC (US) | 2015-12-23 | — | — | EP | disclosed |
| CN-103408480-A | 4-phenyl-pyrrolidone synthesis process | ZHANGJIAGANG WEISHENG BIOLOG PHARMACEUTICAL CO LTD | 2013-11-27 | — | — | CN | disclosed |
| US-8586623-B2 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses | UCB PHARMA, S.A. (BE) | 2013-11-19 | — | — | US | disclosed |
| US-20120295877-A1 | Therapeutic Compounds | GLAXOSMITHKLINE LLC | 2012-11-22 | — | — | US | disclosed |
| US-20120295877-A1 | Therapeutic Compounds | GLAXOSMITHKLINE LLC | 2012-11-22 | — | — | US | disclosed |
| US-20120196866-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses | UCB PHARMA, S.A. (BE) | 2012-08-02 | — | — | US | disclosed |
| US-20120196866-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses | UCB PHARMA, S.A. (BE) | 2012-08-02 | — | — | US | disclosed |
| US-8183241-B2 | 2-oxo-1-pyrrolidine derivatives | UCB PHARMA, S.A. (BE) | 2012-05-22 | — | — | US | disclosed |
| US-8178533-B2 | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses | UCB PHARMA, S.A. (BE) | 2012-05-15 | — | — | US | disclosed |
| WO-2011011652-A1 | THERAPEUTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20090312333-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses | UCB PHARMA, S.A. (BE) | 2009-12-17 | — | — | US | disclosed |
| US-20090156607-A1 | 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB, S.A. (BE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295877-A1 | Therapeutic Compounds | CCR5, CCR1, CXCR3 | GABBR2 1895/4885GABBR1 2597/4885F2 2713/4885 |
| US-20090312333-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses | CYP3A4, CYP1B1, CYP2D6 | GABBR2 2301/4885GABBR1 2356/4885F2 1368/4885 |
| US-20120196866-A1 | 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses | CYP3A4, CYP1B1, CYP2D6 | GABBR2 2301/4885GABBR1 2356/4885F2 1368/4885 |
| US-20090156607-A1 | 2-OXO-1-PYRROLIDINE DERIVATIVES | OPRD1, PPOX, CYP2D6 | GABBR2 1894/4885GABBR1 1913/4885F2 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.