Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.69 |
| ▸ | TTR | P02766 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27710883 | 0.92 | HSPB1 (0.79) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL10363811 | 0.91 | TTR (0.67) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL20328418 | 0.85 | TDP1 (0.66) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL29351649 | 0.85 | TDP1 (0.66) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL20328412 | 0.85 | TDP1 (0.66) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL397931 | 0.85 | TDP1 (0.66) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL1042708 | 0.85 | HSPB1 (0.73) | HSPB1TTRMAPTMEN1KMT2A | |
| SCHEMBL29390372 | 0.85 | HSPB1 (0.73) | HSPB1TTRMAPTMEN1KMT2A | |
| SCHEMBL8973686 | 0.85 | HSPB1 (0.69) | L3MBTL1HSPB1TTRMAPTMEN1 | |
| SCHEMBL1341337 | 0.85 | L3MBTL1 (0.71) | L3MBTL1HSPB1TTRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071344-A2 | NOVEL COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-28 | — | — | WO | disclosed |