Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966296 | 0.89 | TBXA2R (0.56) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27710883 | 0.89 | HSPB1 (0.79) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27721309 | 0.86 | HSPB1 (0.67) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1042708 | 0.85 | HSPB1 (0.73) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29390372 | 0.85 | HSPB1 (0.73) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13236300 | 0.85 | HSPB1 (0.57) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5320033 | 0.85 | L3MBTL1 (0.71) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| Fluoride SCHEMBL27713012 | 0.85 | HSPB1 (0.65) | HSPB1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10422278 | 0.84 | HSD17B10 (0.53) | HSPB1MEN1KMT2AALDH1A1TBXA2R | |
| SCHEMBL8973495 | 0.84 | L3MBTL1 (0.69) | HSPB1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250123-A | Method for preparing 2,4-di(2,4-diamino phenoxy) toluene | UNIV DONGHUA (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-101250124-A | Method for preparing 2,5-di(2,4-diamino phenoxy) toluene | UNIV DONGHUA (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-101245013-A | Process for producing 2,4-bis(2,4-dinitrophenoxy)methylbenzene | UNIV DONGHUA (CN) | 2008-08-20 | — | — | CN | disclosed |
| EP-0335274-B1 | Formation of nitrophenyl ethers from polyols and nitroanisoles | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | disclosed |
| US-4960950-A | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |