Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CDH1 | P12830 | 1/20 | 0.48 |
| ▸ | APC | P25054 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.48 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498373 | 0.86 | CDH1 (0.50) | CYP1A2CYP2C9CYP2C19CDH1APC | |
| SCHEMBL3499455 | 0.86 | SLC2A1 (0.52) | CYP1A2CYP2C9CYP2C19SLC2A2SLC2A1 | |
| SCHEMBL5348158 | 0.85 | AKT1 (0.60) | CYP1A2CYP2C9CYP2C19CDH1APC | |
| SCHEMBL5341132 | 0.84 | CDH1 (0.48) | CYP1A2CYP2C9CYP2C19CDH1APC | |
| SCHEMBL10175208 | 0.82 | GABRA2 (0.53) | SLC2A2SLC2A1NR1I2ABCB11ALB | |
| SCHEMBL5320311 | 0.80 | AKT1 (0.54) | CDH1APCCTNNB1TCF7L2SLC2A1 | |
| SCHEMBL5347759 | 0.79 | AKT1 (0.52) | SLC2A1AKT1AKT2TSPOALDH1A1 | |
| SCHEMBL12128935 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19SLC2A1AKT1 | |
| SCHEMBL21500651 | 0.77 | AKT1 (0.56) | CYP1A2CYP2C9CYP2C19AKT1AKT2 | |
| SCHEMBL2127536 | 0.75 | AKT1 (0.58) | CYP1A2CYP2C9CYP2C19BRD4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | CYP1A2 3046/4885CYP2C9 3267/4885CYP2C19 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.